It has been about ten days since my Mac went all wacky on me and it only functions in Safe Boot mode.
I've since been using it daily for almost everything that I used it before it started acting all wacky in normal mode. I surf the internet, I open and edit all popular Microsoft office formats, I use RapidWeaver to publish on my blog and I download my podcasts on iTunes.

The only limitations are that I cannot use WiFi, I need to be plugged into an ethernet cable, and I don't have any audio. This lead me to think back...back to last January when I upgraded my Dell GX280 from Windows XP to Windows Vista (and office 2007). I must say that my older Mac running in safe boot is actually faster and more usable than a newer Windows PC running Vista! Simply Amazing!